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DEN 117 Aspects of Medical Engineering Tissue Engineering Formal Report Department of Engineering Queen Mary, University of London Written By Poornima Sakthithasan Student No. 050580242 Contents 1. Introduction.................................................................................................3 2. Bone Tissue Engineering.................................................................................3 2.1 Future of Bone-Tissue Engineering 3. Ligament Tissue Engineering ...........................................................................3 3.1 Anatomy and Function 3.2 ACL Replacements 3.3 Current Research 3.4 Future of Ligament Tissue Engineering 4. Cartilage Tissue Engineering............................................................................6 Cartilage Composition Cartilage Response to Injury Clinical Treatment of Cartilage Defects Current Research Future of Cartilage Tissue Engineering 5. Conclusion................................................................................................8 6. References.................................................................................................9 1. Introduction Musculoskeletal disorders are increasing owing to diseases related to ageing and the rising occurrence of sport-related injuries and so there is a need to find an effective approach for the treatment of such orthopaedic disorders. Tissue engineering, a potential field in modern biomedical sciences, because of its combined use of biology, chemistry and principles of engineering, can present successful treatment of musculoskeletal disorders. It uses living cells as engineering materials, such as artificial skin that includes living fibroblasts, cartilage repaired with chondrocytes,...

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