Eight Journal abstracts demonstrating Gene Knock Theory

... Eight Journal abstracts demonstrating Gene Knock Theory 1.Improved methods for the generation of human gene knockout and knockin cell lines Ozlem Topaloglu, Paula J. Hurley, Ozlem Yildirim, Curt I. Civin1,2 and Fred Bunz* Department of Radiation Oncology and Molecular Radiation Sciences, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine Baltimore, MD 21231, USA 1Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine Baltimore, MD 21231, USA 2Department of Pediatrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine Baltimore, MD 21231, USA Received August 11, 2005. Revised September 26, 2005. Accepted September 26, 2005. Recent studies have demonstrated the utility of recombinant adeno-associated viral (rAAV) vectors in the generation of human knockout cell lines. The efficiency with which such cell lines can be generated using rAAV, in comparison with more extensively described plasmid-based approaches, has

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