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Asya Zahra Husnain Dental Biomaterials Essay Any soluble substance can be poisonous for a living organism when present in too high a concentration. Such substances as mercury, arsenic, and beryllium are known as poisons, and no implant containing them can be considered. There is little known with regards to the response induced in tissues due to the following metals: iron, aluminium, chromium, vanadium and cobalt. Tests consisting of lymphocyte blastization have revealed a toxicity scale for metals approximately as follows: Ti ( Stainless steel ( Cr (Ni (Mo (Co (Cu Titanium is the most toxic. This occurs because titanium is not rendered passive by the formation of a TIO2 film (may be monomolecular) which can prevent any autocatalysis reaction that might take place between the metallic atoms of the titanium and the surrounding physiological liquids. Such ions may denature proteins and trigger off immunological responses. They may also gather even in organs positioned far...

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