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The Medicinal Potential of the Poison Dart Frog.  

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The Medicinal Potential of the Poison Dart Frog. Modern medicine is filled with drugs that have been derived from deadly poisons. The potency of these poisons in nature is no accident; each is a part of the organism's defence and predatory mechanisms. Animal venom's make a particularly good source of potential drugs as they are designed to kill or immobilise prey. Many poisons contain dozens or even hundreds of fast acting toxins that home in on muscles and the nervous system. Poisonous snakes, spiders, scorpions and frogs have attracted the most interest, however insects and marine creatures are also a rich source of potent compounds. This essay will discuss the use of the poison dart frog in the search for new chemical entities. Brilliantly coloured frogs of the neotropical family Dendrobatidae produce a variety of novel alkaloids, which have not been detected else where in nature. The family is subdivided into...

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