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Urinary Tract Infections: The Pathogenic Traits of Proteus mirabilis.
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Urinary Tract Infections: The Pathogenic Traits of Proteus mirabilis Sarah Padley ABSTRACT Three pathogenic traits of Proteus mirabilis were looked at. P. mirabilis differentiates from a swimmer state to a swarmer state when in the urinary tract to enable it to migrate up the urinary tract. Chemotaxis enables the cells to determine which direction the kidney is. This investigation found that amino acids gave no chemotactic response, but that certain chemicals did. HCl, KOH and FeSO4 acted as chemorepellants, with glucose and pH7 being chemoattractants. INTRODUCTION Urinary tract infections are common and diverse. Most infections are not serious and are short-lived. Proteus mirabilis is a common soil organism that can cause urinary stones, acute pyelonephritis or cystitis when it infects the urinary tract (1, 2). P. mirabilis has many unique pathogenic traits, but I shall only investigate a few of them. Traits investigated include cell morphology (because it is unique), chemotactic response to amino...
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