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Ribosomes; Structure and function 9 April 2003 Carly Brooks Ribosomes are cytoplasmic organelles discovered in both prokaryotic and eukaryotic organisms. Found in great abundance up to 10,000 in bacterial cells and many times more in eukaryotic cells, they comprise of proteins and rRNA molecules known as subunits, to form a large ribosomal complex. Both eukaryotic and prokaryotic ribosomes in association with transfer RNA (tRNA), act as a site for mRNA translation, assembling a specific sequence of amino acids into polypeptide chains, once the mRNA joins the two component subunits (large and small) of the ribosome. The tRNA is covalently bonded to an individual amino acid and has a complimentary nucleotide sequence, an anticodon, to each mRNA codon which form base pairs, adding specificity to the selection of the corresponding amino acids. The mRNA is linked by hydrogen bonds to the tRNA and is held in proximity to the amino acid so that...

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