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Adaption to Exercise Discuss the metabolic adaptations that occur during prolonged exercise such as a marathon run, and the current views on the possible cause of fatigue in such a situation. 1. Introduction All forms of exercise rely on the body's ability to obtain energy from ingested food, store it until it is needed and then utilise it for the contraction of muscle. Oxidative-phosphorylation is the process by which this occurs, with the oxidation of food eventually resulting in the phosphorylation of ADP and AMP to ATP which is transformed by the muscle into mechanical energy. ATP is generated from different stores in the body depending upon the type of exercise, and its availability depends on the pattern of fibres types, and the availability of oxygen and fuels. There are two main types of muscle fibre, type I (red) and type II (white), each with different characteristics and uses, however their distribution...

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