The effect of aspirin on the action of bovine liver catalase
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The effect of aspirin on the action of bovine liver catalase Introduction Aspirin is a drug commonly used for pain relief and the prevention of heart attacks and strokes. It is readily available over-the-counter and is relatively cheap. The active ingredient in aspirin is acetylsalicylate this compound acts as an antipyretic, anti-inflammatory, anticoagulant and analgesic; this means that is relives pain, fevers, inflammation and prevents blood clots. Aspirin was first discovered around the year 200 B.C. when a Greek called Hippocrates used willow bark (rich in salicin) to relieve pain and fevers. It has since then been refined and compounded to form the modern aspirin. Aspirin works as an enzyme inhibitor, irreversibly binding to prostaglandin synthase, therefore preventing the production of the hormone prostaglandin. The aspirin is believed to bind covalently to the active site of the enzyme prostaglandin synthase, blocking the substrate from entering the active site although the exact action is...

