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0198622 An essay into the various methods of assessing glomerular filtration. The glomerulus is the main filter of the nephron, within the Bowman's capsule. It is semi-permeable, allowing water and soluble wastes to pass through and be excreted out of the Bowman's capsule as urine. The filtered blood passes out of the glomerulus into the efferent arteriole to be returned through the medullary plexus to the intralobular vein. In many renal diseases, it is the glomerulus's ability to filter blood that becomes impaired, and this is why assessing the glomerular function is so important in renal medicine. Glomerular function is assessed by measuring the glomerular filtration rate (GFR). It is frequently measured for initial patient assessment and also patient follow-up for many renal diseases. GFR is measured by performing a clearance study: the renal clearance of any substance represents the theoretical volume of plasma which is completely cleared of that substance in a...

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