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ASPIRIN Abstract An experiment was carried out in which salicylic acid was esterified on its hydroxyl group using acetic anhydride. The product was acetylsalicylic acid, or aspirin, and acetic acid. The esterification was carried out under reflux using concentrated sulphuric acid as catalyst. The product was crystallized and the yield determined to be just over 36%. The melting point of the prepared product was 1140C which differed from the published melting point of 1350C - 1400C Aim The focal aim of the experiment was to perform a chemical reaction to produce acetylsalicylic acid (Aspirin). This was performed as an acetylation of salicylic acid with anhydride. The results of this experiment will allow us to calculate the percentage yield. Introduction Esters are compounds formed by combination of an alcohol with an acid, with a molecule of water being taken out. An esterification is a reaction which achieves this. An example is the production of methyl...

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