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The preparation of 1- Bromobutane
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AS - Level Chemistry Coursework : The preparation of 1- Bromobutane Introduction... Aim : To prepare 1-Bromobutane. Background : The most common way of preparing alkyl halides, which are very useful intermediates in syntheses, is the replacement of the OH group of an alcohol by a halogen. This replacement is a nucleophilic substitution reaction, and alcohols do not undergo nucleophilic substitution reactions because hydroxide ison is strongly basic and a poor leaving group. However, alcohols readily undergo nucleophilic substitutions if the hydroxyl group is first activated to produce a better leaving group, so reaction is carried out in the presence of a strong acid. The acid protonates the alcohol to create a suitable leaving group, water, for the SN2 reaction. Designing... In this experiment 1-butanol will be converted to 1-bromobutane by an SN2 reaction. CH3CH2CH2CH2OH (aq) + HBr (aq) -----> CH3CH2CH2CH2Br (aq) + H2O (l) CH3CH2CH2CH2-OH + HBr CH3CH2CH2CH2-OH2(+) Br(-) CH3CH2CH2CH2-Br + H2O SN2 Reaction is nucleophilic substitution,...
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