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Preparation Of Aspirin Introduction Aspirin (acetylsalicylic acid) is an anti-inflammatory painkiller, which is extensively used, worldwide, for pain relief, to reduce inflammation and temperatures, and to reduce the risk of heart attacks and strokes. Uses of aspirin * Pain relief, particularly where there is inflammation involved, including dental pain and period pain (menorrhagia). * Reducing temperature (as an antipyretic). *Making the blood flow better through narrowed blood vessels. It is prepared by the esterfication of the phenolic hydroxyl group of salicylic acid. The structural formula for aspirin is: Its empirical formula is C9H8O4 Equation The equation for aspirin is: C7H603 + (CH3CO)20 C9H804 Method What I am going to do is * Weigh out 2.0g of 2-hydroxybenzoic acid and place in a 50-cm3 pear shaped flask. * Add 4-cm3 ethanoic anhydride to this. * Add 5 drops of 85% phosphoric acid and swirl to mix. Do this in a fume cupboard. * Reflux the mixture using a boiling water bath for 5 minutes. *...

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