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Topic: Analysing aspirin tablets. I familiarised myself with the Material Safety Data Sheets of toxic substances. PLANNING (A) Aspirin1, or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (to relieve minor aches and pains), antipyretic (to reduce fever), and as an anti-inflammatory. It also has an antiplatelet ("blood-thinning") effect and is used in long-term, low doses to prevent heart attacks and cancer. figure 1 figure 2 Aspirin tablets consist mainly of 2-ethanoylhydroxybenzoic acid (acetylsalicylic acid, CH3COOC6H4COOH, figure 3). figure 3 Although the acidic conditions found in stomach do not affect aspirin, the alkaline juices in the intestines hydrolyse it to ethanoate (acetate) ions and 2-hydroxybenzoate ions. CH3COOC6H4COOH + 2OH- › CH3COO- + HOC6H4COO- + H2O Aim: To determine the percentage of CH3COOC6H4COOH in aspirin tablets. Hypothesis: When a known amount of standard sodium hydroxide solution is used in excess to hydrolyse a known mass of aspirin tablets, we may determine the...

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