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Heart attacks occur when the blood supply to a portion of the heart muscle (myocardium) is severely reduced or stopped. This occurs when one of the arteries that supply blood to the heart muscle (coronary arteries) is blocked by an obstruction. This blockage can be due to atherosclerosis (a build-up of deposits of fat-like substances), a blood clot (coronary thrombosis), or a coronary vessel spasm coupled with a near total obstruction. If the blood supply to a portion of the heart stops, that portion will no longer receive the oxygen or nutrients necessary to carry out its function and will die. If a very small part of the heart is affected, the heart will be able to continue working without it. However, if a large enough portion is damaged, irreversible damage can result, leading to death. The pain of a heart attack is the result of heart tissue ischemia...

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