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Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Urinary Bladder Postgraduate Certificate in Health Science HEAL 8010 Advanced Therapy Technology Assignment 2 Mooi Tin Khaw POSTGRAD - RT Student ID 1195808 June 2004 Mucosa -associated lymphoid tissue (MALT) are specialised lymphoid tissue that evolved to protect permeable mucosal sites such as the gastrointestinal tract and the bronchi that are directly in contact with the external environment (Isaacson & Norton, 1994). MALT lymphoma was first isolated in 1983 by Isaacson and Wright from 2 cases of low grade B-cell gastrointestinal lymphoma (Thieblemont, 1995). It is a distinctive type of malignant B-cell lymphoma (Tsang et al, 2001). Literature review showed that MALT lymphomas also arise at sites such as lung, trachea, thymus, skin, gall bladder, salivary glands and bladder. MALT lymphoma is now incorporated into the Revised European-American Lymphoma (REAL) and the World Health Organisation (WHO) classification systems as extranodal marginal zone B-cell lymphoma. (Tsang et al, 2001). Isaacson & Norton (1994) reported 13%...

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