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Topic: Drugs Abuse Drug dependence. People who repeatedly take large amounts of such drugs as alcohol, amphetamines, barbiturates, or narcotics may become dependent on the drugs. These people have an intense psychological or physical need for a drug's effects. Tolerance, or resistance to a drug's effects, usually develops along with drug dependence. As drug use continues, tolerance increases. The drug user must thus take larger and larger doses to obtain the desired effects. The development of physical or psychological dependence, or both, is commonly called drug addiction. In most cases, a severe withdrawal illness occurs if a person stops taking the drug. See DRUG ABUSE. Elimination from the body. The body eliminates drugs with other waste materials. Most drugs travel from the cells through the bloodstream to the kidneys and are eliminated in the urine. The body also eliminates drugs in sweat, tears, and solid wastes. Some anesthetics are eliminated almost...

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