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Sickle cell anaemia The disorder affects the red blood cells, which contain a special protein called haemoglobin . The function of haemoglobin is to carry oxygen from the lungs to all parts of the body. People with Sickle Cell Anaemia have Sickle haemoglobin which is different from the normal haemoglobin. When sickle haemoglobin gives up its oxygen to the tissues, it sticks together to form long rods inside the red blood cells making these cells rigid and sickle-shaped. Normal red blood cells can bend and flex easily. Because of their shape, sickled red blood cells can't squeeze through small blood vessels as easily as the almost donut-shaped normal cells. This can lead to these small blood vessels getting blocked that then stops the oxygen from getting through to where it is needed. This in turn can lead to severe pain and damage to organs. Everyone has two copies of the gene for haemoglobin;...

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