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Discuss mechanisms of viral persistence illustrating your answer with specific examples Viruses have acquired mechanisms to persist in human hosts even if antiviral drugs are applied to block significant stages in the virus cycle. Strategies are developed by viruses to 'evade, escape and survive' to fight against the host's immune system so that pathogens are able to persists and their purpose can be continued. Usually this type of strategy is employed by the 'hit and stay' viruses and their ultimate aim is to gain long residence in the host's body. Viral reservoirs represent a major problem with terminating infections as the drugs are no longer effective in virus clearance. This could lead to chronic infections, which can be divided into two kinds: The chronic persistent infection and viral latency. In the first type there is continuous replication of the virus from the time of the host being infected primarily and usually...

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