A Circulatory Disease: Sickle Cell Anaemia
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A Circulatory Disease: Sickle Cell Anaemia Sickle Cell Anaemia isn't really a "disease" like AIDS or TB; it is more of a disorder. The main factor in this disorder is a protein called Haemoglobin. This protein is found in all red blood cells (erythrocytes1), and it is used fort he transportation of oxygen around the body to places where it is needed for respiration I.e. cells. As Haemoglobin is a protein it consists of one or more polypeptide chains that are folded into a complex three-dimensional shape. The shape is determined by the arrangement of the amino acids in the polypeptide chains. Haemoglobin is an example of a quaternary structured protein in that it is made up of more than one polypeptide chain. Each molecule of haemoglobin is consisted of up to four polypeptide chains. From the diagram you can clearly see that the shape of the haemoglobin molecule is rounded,...

