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Mutation and its Consequences - Gene mutations occur when there is change in the sequence of bases, such as when the gene is copied incorrectly.
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Asif Khan 12-B1 Mutation and its Consequences Gene mutations occur when there is change in the sequence of bases, such as when the gene is copied incorrectly. This can result in one or more different amino acids depending on how the mutation occurs. There are three ways a mutation could occur:> Substitution o Substitution occurs when the wrong gene is inserted in to base sequence. Original base sequence: AGC TAC GTA CGT This transcribes into: UCG AUG CAU GCA These code into the following amino acids: Serine - Methionine - Histidine - Alanine. If one base were to be substituted, the DNA sequence would then read: AGC TAC GTA AGT. The last codon will now be transcribed as UCA which translates into the amino acid Serine. Because the primary structure has now been changed, this may affect the tertiary and quaternary structures.> Addition o Addition occurs when an extra base is added into the sequence. All the...
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